Welcome to the WLM Public Website!

WLM was a randomized clinical trial funded by the National Heart, Lung, and Blood Institute (NHLBI).
  • Phase I was a 6-month initial weight loss intervention
    • 1685 participants
    • Began in August 2003 and ended in December 2004
  • Phase II was a randomized 30-month trial that compared two alternate maintenance strategies - personal contact and interactive technology - to a control condition
    • 1032 participants (those who lost 4 kg in Phase I)
    • Began in February 2004 and ended in June 2007
WLM participating institutions included the following:
  • Four clinical centers:
    • Duke University
    • Johns Hopkins University
    • Pennington Biomedical Research Center
    • Center for Health Research, Kaiser Permanente Northwest
  • A coordinating center: Center for Health Research, Kaiser Permanente Northwest
  • NHLBI
The WLM protocol was approved by an Institutional Review Board at each participating site and by an NHLBI-appointed Protocol Review Committee. All participants provided written informed consent.








© Copyright 2007, Kaiser Permanente Center for Health Research, Portland, Oregon. All rights reserved. Permission is granted, without costs to the Weight Loss Maintenance (WLM) trial or to the public, for access to these materials. The manuals may be downloaded, duplicated, transmitted and otherwise distributed for non-commercial educational or research purposes only, provided proper credit is given to the WLM Research Group.
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