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| Study Objectives & Protocol |
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Primary Objectives
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Measure the prevalence of COPD and its risk factors in various countries around
the world.
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Estimate the burden of COPD in terms of its impact on quality of life, activity
limitation, respiratory symptoms, and use of health care services.
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Develop a validated model to project future burden of disease for COPD.
Secondary Objectives
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Compare the impact on COPD prevalence of using various definitions of COPD,
including those proposed by the American Thoracic Society (1), The European
Respiratory Society (2), and GOLD (3).
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Determine the extent to which variations in risk factors contribute to
variations in the prevalence of COPD.
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Describe the distribution of COPD according to age, sex, and smoking history.
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Describe the main clinical symptoms reported by subjects diagnosed with COPD.
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Assess the sensitivity and specificity of selected clinical symptoms for COPD
using lung function as the gold standard.
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Characterize the clinical management of COPD in selected broad geographic
areas.
Download
the BOLD protocol (Adobe PDF document)
BOLD Project Summary of Objectives and Methods
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