Evelyn P. Whitlock, MD, MPH

Director, Kaiser Permanente Research Affiliates Evidence-based Practice Center
Senior Investigator, CHR Northwest
Evelyn Whitlock

Dr. Whitlock is a Senior Investigator at The Center for Health Research (TCHR); a board-certified preventive medicine physician; and Director of Kaiser Permanente Research Affiliates Evidence-based Practice Center (KPRA EPC). Her main focus is evidence-based medicine and policy.

The KPRA EPC is one of 11 officially designated EPCs in the nation and is under a multi-year contract to the Agency for Healthcare Research and Quality (AHRQ) to produce evidence syntheses based on systematic reviews, lead methodological development for systematic reviews, and support the increased application of systematic reviews and other evidence-based products into policy and practice. The EPC involves 79 researchers from three integrated health care delivery systems, including Kaiser Permanente, Group Health, and Health Partners.

Dr. Whitlock serves as the Principal Investigator for the United States Preventive Services Task Force (USPSTF) contract, an EPC program that systematically reviews the evidence to support USPSTF recommendations for clinical preventive services. She is also co-Principal Investigator of AHRQ’s Scientific Resource Center for its Effective Healthcare Program and leads the Topic Triage group, which evaluates topics nominated for systematic review in comparative effectiveness.

Dr. Whitlock was a member of the senior faculty of the Oregon Clinical and Translational Research Institute (OCTRI), one of 12 NIH-funded awards for Clinical and Translational Sciences, and helped develop and implement OCTRI's Translation of Research into Policy and Practice Program. She previously served as the Portland clinical site PI and Medical Director for the Women's Health Initiative and is now a co-investigator. Dr. Whitlock has significant experience conducting clinical trials, epidemiological studies, and health-services research using large observational datasets, survey data, and administrative datasets. Other recent research includes a collaboration with the CDC that created and validated an algorithm to determine pregnancy episodes and their outcomes within Kaiser Permanente Northwest, with ongoing work investigating important public health issues during pregnancy.

In addition to her appointment at CHR, Dr. Whitlock is an adjunct associate professor in OHSU’s Department of Medical Informatics and Clinical Epidemiology. She also serves as a clinical associate professor in the Department of Health and Preventive Medicine at OHSU , where she directed the Residency Program from 1993-1997.

E-mail: Evelyn.Whitlock@kpchr.org

Recent Publications:

Goddard KA, Whitlock EP, Berg JS, Williams MS, Webber EM, Webster JA, Lin JS, Schrader KA, Campos-Outcalt D, Offit K, Feigelson HS, Hollombe C. Description and pilot results from a novel method for evaluating return of incidental findings from next-generation sequencing technologies. Genetics in Medicine 2013 Apr 4. [Epub 2013 Apr 4]   PubMed abstract
O'Connor EA, Gaynes BN, Burda BU, Soh C, Whitlock EP. Primary Care: A Systematic Review for the U.S. Preventive Services Task Force. Annals Internal Medicine [Epub 2013 Apr 23].  
Eckstrom EN, Feeny DH, Walter LC, Perdue LA, Whitlock EP. Individualizing cancer screening in older adults: A narrative review and framework for future research. Journal of General Internal Medicine 2012 Sept 28. [Epub ahead of print] PMID: 23054920 PMC3614148   Full text
Eder M, Feightner A, Webber E, Guirguis-Blake J, Whitlock EP. Developing and selecting topic nominations for systematic reviews. Methods Research Report. No. 12(13)-EHC153-EF. (Prepared by Oregon Evidence-based Practice Center under Contract No. HHSA 290-2007-10057-I.) Rockville, MD: Agency for Healthcare Research and Quality. November 2012. www.effectivehealthcare.ahrq.gov/reports/final.cfm.  
Goddard KAB, Knaus WA, Whitlock EP, Lyman GH, Feigelson HS, Schully S, Ramsey S, Tunis S, Freedman AN, Khoury MJ, Veenstra DL. Building the evidence base for decision making in cancer genomics using comparative effectiveness research. Genetics in Medicine 2012 Jul; 14(7):633-42. [Epub 2012 Apr 19]    Full text
Jackson JM, Defor TA, Crain AL, Kerby T, Strayer L, Lewis CE, Whitlock EP, Williams S, Bonds DE, Vitolins MZ, Rodabough RJ, Margolis KL. Self-reported diabetes is a valid outcome in pragmatic clinical trials and observational studies. J Clin Epidemiol. 2012 May 5. [Epub ahead of print] PMC Journal - In Process   PubMed abstract
Lin JS, Thompson M, Goddard KAB, Piper M, Heneghan C, Whitlock EP. Evaluating genomic tests from bench to bedside: a practical framework. BMC Medical Informatics and Decision Making. 2012 Oct 19;12(1):117. [Epub ahead of print] PMC3538070   Full text
Lin JS, Webber EM, Beil TL, Goddard KA, Whitlock EP. Fecal DNA Testing in Screening for Colorectal Cancer in Average Risk Adults. Comparative Effectiveness Review No. 52. AHRQ Publication No. 12-EHC022-EF. Agency for Healthcare Research and Quality, Rockville, MD. February 2012.  
Lin JS, Whitlock EP, Eckstrom E, Fu R, Perdue L, Beil T, Leipzig R. Challenges in synthesizing and interpreting the evidence from a systematic review of multifactorial interventions to prevent functional decline in older adults. Evidence Syntheses/Technology Assessment, No. 94. AHRQ Publication No. 12-05169-EF-1. Agency for Healthcare Research and Quality, Rockville, MD. October 2012  
Lin JS, Whitlock EP, Eckstrom E, Fu R, Perdue LA, Beil TL, Leipzig. Challenges in synthesizing and interpreting the evidence from a systemic review of multifactorial interventions to prevent functional decline in older adults. Journal of the American Geriatrics Society 2012 Nov; 60(11):2157-66. [Epub 2012 Oct 16]   PubMed abstract


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