Study Details

Study of Osteoporotic Fractures—SOF

Teresa A. Hillier, Principal Investigator
Kimberly K. Vesco, Co-Principal Investigator

The Study of Osteoporotic Fractures (SOF) is a four-center study funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases. SOF is a prospective cohort study of a group of initially healthy women, 65 years or older, to determine what factors lead to the development of osteoporosis. This study identifies risk factors for hip and wrist fractures and changes in bone density. SOF began in 1986 with the recruitment and examination of more than 9,700 women 65 years or older. SOF is continuing to study this group of women. It examined how changes in bone density affect the risk of fractures, as well as what factors predict changes in bone density. In addition, the study is currently examining surviving SOF participants in their residences to assess several dimensions of cognitive function and determine why some women achieve exceptional cognitive function and mobility after age 85.
Funding source: National Institute of Arthritis and Musculoskeletal and Skin Diseases

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