You’re invited to join a research study for a C. diff vaccine!
Thank you for your interest in Beethoven. This research study, sponsored by Pfizer, will evaluate the safety and effectiveness of an investigational vaccine against Clostridioides difficile (C. diff) for adults ages 65 and over. An investigational vaccine is one that has not yet been approved by the Food and Drug Administration (FDA) for use by the general public.
Click here to see if you are eligibleWhat is C Diff?
C. Diff is a bacteria that can spread from one person to another causing severe diarrhea, fever, nausea, and blood in the stool. Serious infections can be life threatening. People 65 and older who recently took antibiotics or are being treated at a hospital or clinic have a higher chance of getting sick from C. diff. Currently, there is no approved vaccine to prevent illness caused by C. diff.
Who can join?
You may be eligible to take part in this study if you:
- Are 65 or older
- Are willing and able to receive 2 vaccines
- Have never had a C. diff infection
- Are willing to attend 5 in-person visits and remain in the study for up to 3.5 years
What is involved?
If you choose to participate, you will be:
- Randomly assigned (by chance) to receive either the investigational vaccine or a placebo (saline)
- Asked to complete at least 5 office visits, 2 of which will include vaccination
- Asked to report diarrhea symptoms for up to 3.5 years
- Compensated for your time:
- $50 per phone visit
- $150 per on-site visit
- Up to $10 per month for completion of a diarrhea electronic diary
- Up to $75 if asked to complete a vaccination electronic diary
- $150 if asked to complete a visit and submit a stool sample during a diarrheal episode
How do I enroll?
First, go here to see if you may be eligible: